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Prevalence of Multi-drug Resistant Acinetobacter baumannii (MDRAB) in Amman Jordan During 2018

Author(s):

Layla El-khatib, Saed Al-dalain, Rama Al-Matarneh, Sara Al-Bustanji, Marwa Al-Dmour, Yara Al-Amarin and Yasser Gaber*   Pages 1 - 7 ( 7 )

Abstract:


Purpose: Acinetobacter baumannii is as an opportunistic pathogen, and is among the most problematic nosocomial infections as well as community acquired infections. This retrospective study was conducted as an attempt to determine the prevalence of multidrug-resistant A. baumannii (MDRAB) isolates from north and central Jordan area during 2018.

Methods: Patients records provided by an accredited central private laboratory located in Amman, were inspected for A. baumannii isolates identified during this period. The isolates were identified to the species level using API-10S system and the antimicrobial sensitivity testing was determined using Kirby–Bauer disc diffusion method.

Results: A total of 43 unduplicated isolates were obtained and classified according to clinical sampling source into: Group I (blood), Group II (urine) and Group III (wound, pus, sputum, bed-sore and others). Total MDRAB recorded were 32 isolates (74.4 %). Resistance to imipenem were 36% and 94% among groups II and III respectively, and resistance to meropenem were 60% and 88% among the same groups respectively.

Conclusion: Antimicrobial stewardship programs at a national scale are needed to calculate the actual proportion of MDRAB in the country and to combat its increasing emergence and decrease the magnitude of antibiotic resistance.

Keywords:

Resistance, Antibiotic, Acinetobacter, Colistin, Mutlidrug-Resistance, Imipenem

Affiliation:

Department of Biological sciences, School of Science, The University of Jordan, Amman, 11942, Department of Pharmacology, Faculty of Medicine, Mutah University, Al-Karak, 61710, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Mutah University, Al-karak, 61710, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Mutah University, Al-karak, 61710, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Mutah University, Al-karak, 61710, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Mutah University, Al-karak, 61710, Department of Microbiology and Immunology, Faculty of Pharmacy, Beni-Suef University, 62511, Beni-Suef



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