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Linezolid Resistance in Staphylococcus Haemolyticus - Case Series and Review of Literature

Author(s):

Varsha Gupta, Neelam Gulati, Shiwani Sharma*, Ravi Gupta, Ashwani Soni and Jagdish Chander   Pages 1 - 5 ( 5 )

Abstract:


Coagulase negative Staphylococci are important The common antibiotics used for the treatment of the infections caused by CoNS are penicillins, oxacillin, ciprofloxacin, clindamycin, erythromycin, gentamicin, and vancomycin. Linezolid is an oxazolidinone group of antibiotic with activity against Gram-positive bacteria. It is used for the treatment of serious infections caused by Gram-positive bacteria resistant to other antibiotics, including streptococci, vancomycin-resistant enterococci (VRE). The common antibiotics used for the treatment of the infections caused by CoNS are penicillins, oxacillin, ciprofloxacin, clindamycin, erythromycin, gentamicin, and vancomycin. Linezolid is approved as an alternative drug to be given for catheter-related bloodstream infections. In earlier studies, linezolid-resistant staphylococci have been reported increasingly all over the world. We are discussing five cases of Linezolid resistant Staphylococcus haemolyticuswhich were reported in our laboratory during one year from patients with devicerelated infections and also review of literature is being presented for an update. This study emphasizes the judicious use of newer antibiotics to contain the spread of resistance.

Keywords:

Coagulase negative Staphylococci, antibiotics, drug resistance.

Affiliation:

Department of Microbiology, Govt. Medical College and Hospital, Department of Microbiology, Govt. Medical College and Hospital, Department of Microbiology, Govt. Medical College and Hospital, Department of Microbiology, Govt. Medical College and Hospital, Department of Orthopedics, Govt. Medical College and Hospital, Department of Microbiology, Govt. Medical College and Hospital



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