Submit Manuscript  

Article Details


A Case of Subcutaneous Phaeohyphomycosis Associated with Leprosy

[ Vol. 17 , Issue. 3 ]

Author(s):

Márcia M. R. Teixeira, Claudia B. Assunção, Sandra Lyon, Renata R. Gomes, Hyllo B.M. Junior, Fabiana Rocha-Silva, Sônia M. de Figueiredo, Amanda Sanchez Machado, Elen R.R. Teixeira, Adriana S. Carneiro, Rogério J.M.B. Júnior, Vânia A. Vicente and Rachel B. Caligiorne*   Pages 223 - 226 ( 4 )

Abstract:


Background: Subcutaneous phaeohyphomycosis is an infection caused by melanized fungi and is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak.

Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of the secretion, with subsequent direct mycological observations, culture and molecular analysis. The species agent was identified by culture and nucleotide sequences of ribosomal DNA as Exophiala dermatitidis.

Keywords:

Dermatomycoses, leprosy, phaeohyphomycosis, Exophiala dermatitidis, mycological, DNA.

Affiliation:

Faculdade de Medicina da Universidade Federal de Minas Gerais, MG, Núcleo de Pós-Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG, Serviço de Dermatologia do Hospital Eduardo de Menezes, Fundação Hospitalar do Estado de Minas Gerais, Microbiology, Parasitology and Pathology Post-graduation Program, Department of Basic Pathology, Federal University of Parana, PR, Serviço de Dermatologia do Hospital Eduardo de Menezes, Fundação Hospitalar do Estado de Minas Gerais, Núcleo de Pós-Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG, Núcleo de Pós-Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG, Núcleo de Pós-Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG, Faculdade de Medicina da Universidade Federal de Minas Gerais, MG, Faculdade de Medicina da Universidade Federal de Minas Gerais, MG, Faculdade de Medicina da Universidade Federal de Minas Gerais, MG, Microbiology, Parasitology and Pathology Post-graduation Program, Department of Basic Pathology, Federal University of Parana, PR, Núcleo de Pós- Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG

Graphical Abstract:



Read Full-Text article